Extracellular Matrix and Ground Regulation
Posted on Dec 4th, 2007
by
Albert
Animated by a recent article of Photizo about Oxidative Stress and Antioxidants I want to inform about a newly published (and translated) book of Austrian explorer and Professor Alfred Pischinger. I am convinced its highly relevant not only for therapists , doctors of all kind, but for all intreested in Wellness, Fitness, Sports, Yoga, Rehabiltation, prevention and vibrant health. For all interested in LOHAS, in everything which is even slightly connected to integral, holistic, evolutionary approach to health and vibrant vitality.
This ECM is a living space of fluid with multiple exchange processes between the cells and the Interstitium. With a volume of roundabout 15 -17 litres twice as much as the total sum of blood for example. Imagaine an aqaurium where teh fishes (organ cells) never touch but their activities are always immersed in. Thousands of echange proceses between cell membranes and this space take place evey second. And this transit section is no passive room. Its highly dynamic and pervades as mesenchym the whole human organism.
I saw -again provided by Photizo - a wonderful animation video from Harvard students about behavior of human cells.
Animation takes Harvard Students on a 3 D Story
The same animation would be most astonishing when the ECM and processes of ground regulation would be visulaized! It would be a journey through the whole universe of the organism. Not, as usually known via Nervous System or blood circulation. Not limited to local mechanisms. The real exchange between oxygen and CO2, between thousands of nutritients, toxins, cell garbage, deposits and metabolic products of all kind is happening in this space. And all sequences of healing as much as loosing organic balances are conneced to the Extracellular Matrix.
So there can be no holistc understanding of the cell processes without an in depth understanding of the ECM and its most complex dynamics! Pathogenesis as much as salutogenesis on the cell level need exploration of exchange processes BETWEEN organ cells and the Interstitium Matrix.
When I studied medicine I wanted to develop for masters thesis a kind of integrated theory for medicine. Including biology, Chinese Medicine, Ayurveda, psychosomatic medicine, alternative and complimentary approaches, conventional cell theory, eastern and Western Healing Approaches and at least 100 existing perspectives of iot all.
Dropped this endevor....but this work of Alfred Pisichinger ALWAYS catched my attention and I am very happy to see his profound work finally making its way to the Anglo-Saxon language sphere. Higly recommended! My personal wish is that this approach will enter the world of academic medical crowds some day and serve for major breakthroughs in mainstream research of brain/mind medicine. The theory of Extracellular Matrix serves also as great framework for the research about bio-photones and ultra-fast cell communication, provided by
Fritz Albert Popp
Extracellular Matrix and Ground Regulation
From the Publisher
The workings of the suitable environment for cells-called the extracellular matrix (ECM) and ground regulation-has occupied the European medical tradition since the early part of the 20th century. As it has become more clear that the origin of disease and its first signals register in the connective tissue, or myofascia, cellular pathologists and biochemists have sought to circumscribe networks of cell communication and microcirculation in the ECM. Alfred Pischinger (1899-1982) continued this ...+ read moreThe workings of the suitable environment for cells-called the extracellular matrix (ECM) and ground regulation-has occupied the European medical tradition since the early part of the 20th century. As it has become more clear that the origin of disease and its first signals register in the connective tissue, or myofascia, cellular pathologists and biochemists have sought to circumscribe networks of cell communication and microcirculation in the ECM.
Alfred Pischinger (1899-1982) continued this line of work by further studying, in work published from 1926 through the late seventies, the connections of the ECM to the hormonal and autonomic systems. In the last twenty years Professor and Doctor of Natural Sciences Hartmut Heine and his colleagues have carried on Pischinger's work, here summarized in one volume. Part One encompasses theoretical underpinnings; Parts Two and Three address applications and directions for further research.
This updated English-language translation not only is an account of the work of Pischinger's successors-Heine, Otto Bergsmann, and Felix Perger, (the three editors of this volume) and their many colleagues-but notes the positive development of complementary therapies based on this understanding of histology. Acupuncture is referenced directly. Both in Europe and the States the work of manual therapists, including Rolfers, cranio- sacral therapists, and other somatic disciplines have been informed for many years by Pischinger's outsider model of how changes in the EMC register in the central nervous system and the brain, and are conveyed back to the periphery and connected organs. Heine's exciting recent work shows that the regulation and construction of the ECM have relationships to cybernetic non-linear systems and phase transitions.- read less
About the Author
Author Alfred Pischinger was the first scientist to develop a theory for complementary (holistic) medicine based on the regulation of the extracellular matrix (ground regulation). He was born in Linz, Austria in 1899 and died in 1983 in Graz.Editor Hartmut Heine was appointed Professor of Anatomy at the University of Wurzburg Germany in 1976 and in 1982 became full professor at Witten/Herdecke University. Currently residing near Stuttgart, Germany, Heine is a Doctor of Natural Sciences focused ...+ read moreAuthor Alfred Pischinger was the first scientist to develop a theory for complementary (holistic) medicine based on the regulation of the extracellular matrix (ground regulation). He was born in Linz, Austria in 1899 and died in 1983 in Graz.
Editor Hartmut Heine was appointed Professor of Anatomy at the University of Wurzburg Germany in 1976 and in 1982 became full professor at Witten/Herdecke University. Currently residing near Stuttgart, Germany, Heine is a Doctor of Natural Sciences focused on comparative anatomy.
Translator Ingeborg Eibl studied music and pre-med at McGill University and later graduated from New York Chiropractic College and Ontario College of Naturopathic Medicine. She has a chiropractic practice in Rochester, New York.
This ECM is a living space of fluid with multiple exchange processes between the cells and the Interstitium. With a volume of roundabout 15 -17 litres twice as much as the total sum of blood for example. Imagaine an aqaurium where teh fishes (organ cells) never touch but their activities are always immersed in. Thousands of echange proceses between cell membranes and this space take place evey second. And this transit section is no passive room. Its highly dynamic and pervades as mesenchym the whole human organism.
I saw -again provided by Photizo - a wonderful animation video from Harvard students about behavior of human cells.
Animation takes Harvard Students on a 3 D Story
The same animation would be most astonishing when the ECM and processes of ground regulation would be visulaized! It would be a journey through the whole universe of the organism. Not, as usually known via Nervous System or blood circulation. Not limited to local mechanisms. The real exchange between oxygen and CO2, between thousands of nutritients, toxins, cell garbage, deposits and metabolic products of all kind is happening in this space. And all sequences of healing as much as loosing organic balances are conneced to the Extracellular Matrix.
So there can be no holistc understanding of the cell processes without an in depth understanding of the ECM and its most complex dynamics! Pathogenesis as much as salutogenesis on the cell level need exploration of exchange processes BETWEEN organ cells and the Interstitium Matrix.
When I studied medicine I wanted to develop for masters thesis a kind of integrated theory for medicine. Including biology, Chinese Medicine, Ayurveda, psychosomatic medicine, alternative and complimentary approaches, conventional cell theory, eastern and Western Healing Approaches and at least 100 existing perspectives of iot all.
Dropped this endevor....but this work of Alfred Pisichinger ALWAYS catched my attention and I am very happy to see his profound work finally making its way to the Anglo-Saxon language sphere. Higly recommended! My personal wish is that this approach will enter the world of academic medical crowds some day and serve for major breakthroughs in mainstream research of brain/mind medicine. The theory of Extracellular Matrix serves also as great framework for the research about bio-photones and ultra-fast cell communication, provided by
Fritz Albert Popp

(Abbildung: Der Stoffwechsel im weichen Bindegewebe oder das sogenannte Grundregulationssystem nach Pischinger)
Extracellular Matrix and Ground Regulation
From the Publisher
The workings of the suitable environment for cells-called the extracellular matrix (ECM) and ground regulation-has occupied the European medical tradition since the early part of the 20th century. As it has become more clear that the origin of disease and its first signals register in the connective tissue, or myofascia, cellular pathologists and biochemists have sought to circumscribe networks of cell communication and microcirculation in the ECM. Alfred Pischinger (1899-1982) continued this ...+ read moreThe workings of the suitable environment for cells-called the extracellular matrix (ECM) and ground regulation-has occupied the European medical tradition since the early part of the 20th century. As it has become more clear that the origin of disease and its first signals register in the connective tissue, or myofascia, cellular pathologists and biochemists have sought to circumscribe networks of cell communication and microcirculation in the ECM.
Alfred Pischinger (1899-1982) continued this line of work by further studying, in work published from 1926 through the late seventies, the connections of the ECM to the hormonal and autonomic systems. In the last twenty years Professor and Doctor of Natural Sciences Hartmut Heine and his colleagues have carried on Pischinger's work, here summarized in one volume. Part One encompasses theoretical underpinnings; Parts Two and Three address applications and directions for further research.
This updated English-language translation not only is an account of the work of Pischinger's successors-Heine, Otto Bergsmann, and Felix Perger, (the three editors of this volume) and their many colleagues-but notes the positive development of complementary therapies based on this understanding of histology. Acupuncture is referenced directly. Both in Europe and the States the work of manual therapists, including Rolfers, cranio- sacral therapists, and other somatic disciplines have been informed for many years by Pischinger's outsider model of how changes in the EMC register in the central nervous system and the brain, and are conveyed back to the periphery and connected organs. Heine's exciting recent work shows that the regulation and construction of the ECM have relationships to cybernetic non-linear systems and phase transitions.- read less
About the Author
Author Alfred Pischinger was the first scientist to develop a theory for complementary (holistic) medicine based on the regulation of the extracellular matrix (ground regulation). He was born in Linz, Austria in 1899 and died in 1983 in Graz.Editor Hartmut Heine was appointed Professor of Anatomy at the University of Wurzburg Germany in 1976 and in 1982 became full professor at Witten/Herdecke University. Currently residing near Stuttgart, Germany, Heine is a Doctor of Natural Sciences focused ...+ read moreAuthor Alfred Pischinger was the first scientist to develop a theory for complementary (holistic) medicine based on the regulation of the extracellular matrix (ground regulation). He was born in Linz, Austria in 1899 and died in 1983 in Graz.
Editor Hartmut Heine was appointed Professor of Anatomy at the University of Wurzburg Germany in 1976 and in 1982 became full professor at Witten/Herdecke University. Currently residing near Stuttgart, Germany, Heine is a Doctor of Natural Sciences focused on comparative anatomy.
Translator Ingeborg Eibl studied music and pre-med at McGill University and later graduated from New York Chiropractic College and Ontario College of Naturopathic Medicine. She has a chiropractic practice in Rochester, New York.
Tagged with: Alfred Pischinger, Homeopathy, Austria, University of Witten Herdecke, Medicine, MyGill Univesity, ONtario Colege of Naturopathic Medicine, Comparative Anatomy, Rolfing, Yoga, Health, Wellness, EPS, Connective Tissue, Cellular Pathology, Micro Circulation, European Medical Tradition, Histology, Acupunture, Cranio-sacral Therapists.







